Views: 0 Author: Site Editor Publish Time: 2022-06-29 Origin: Site
Pipemidicacid (Acidopipemidico) is a class of pyridopyrimidine antibiotics that are derivatives of piromidicacid and are active against Gram-negative and some Gram-positive bacteria.
Chemical properties light yellow crystalline powder. Melting point 251-255℃ (decomposition). Soluble in glacial acetic acid, insoluble in methanol, acetone, DMF, extremely insoluble in water, ethanol, chloroform, insoluble in benzene, soluble in dilute alkali or acid solution. Odorless, bitter taste.
It is a representative of the second generation of quinolones antibacterial drugs, with a wider antibacterial spectrum compared with nalidixic acid, used for urinary tract infections and ENT infections, etc. It has a strong antibacterial effect on Pseudomonas aeruginosa, Escherichia coli, Bacillus dysenteriae and other gram-negative bacilli, and is used for the treatment of acute urinary tract infections and other conditions.