Online

Cart
You are here: Home » Products » Pharmaceutical Ingredient » Antiparasitic » High quality USP/EP/BP GMP DMF FDA Albendazole Oral Suspension CAS NO 54965-21-8 producer
Share to:

High quality USP/EP/BP GMP DMF FDA Albendazole Oral Suspension CAS NO 54965-21-8 producer

5 0 Reviews

Price: $ 0.08 / pcs
Quantity:
min order: 1 pcs
View wholesale prices
  • Quantity Price
  • 1 $0.5
  • 10000 $0.2
  • 100000 $0.1
  • 300000 $0.08
  • AZ555
  • Dideu
  • 54965-21-8
  • C12H15N3O2S
  • 259-414-7
  • China
  • Oral Suspension
  • High quality
  • 99.0% Min
  • 99%-101%
  • Oral Suspension
  • Solubility in water
  • 1.0% max
  • 0.5% Max
  • 10 ppm Max
  • H-NMR
  • 0.5% Max
  • Medicine

Our Reference Specification, for more details, pls contact us for COA,MSDS and certification:

Email & Skype: support@dideu.com  Telephone:+86-29-89586682

Mobile:+86-15129568250; Whatsapp: +8615129568250

Albendazole Oral Suspension 

Action and use

Benzimidazole antihelminthic.

Definition

Albendazole Oral Suspension is a suspension of Albendazole in a suitable vehicle.

The oral suspension complies with the requirements stated under Oral Liquids and with the following requirements.

Content of albendazole, C12H15N3O2S

90.0  to 110.0% of the stated amount.

Identification

A.  To a volume of oral suspension containing 25 mg of Albendazole add 50 ml of 0.1M sodium hydroxide and shake with the aid of ultrasound for 10 minutes. Dilute to 100 ml with the same solvent, filter through a 0.45-µm filter and dilute 1 volume of this solution to 10 volumes with the same solvent. The light absorption, Appendix II B, in the range 240 to 340 nm of the resulting solution exhibits a maximum at 308 nm, a minimum at 281 nm and a shoulder at 269 nm.

B.  To a volume of oral suspension containing 25 mg of Albendazole add 50 ml of 0.1M hydrochloric acid and shake with the aid of ultrasound for 10 minutes. Dilute to 100 ml with the same solvent, filter through a 0.45-µm filter and dilute 1 volume of this solution to 10 volumes with the same solvent. The light absorption, Appendix II B, in the range 240 to 340 nm of the resulting solution exhibits a maximum at 292 nm, a minimum at 273 nm and a shoulder at 261 nm.

C.  In the Assay, the chromatogram obtained with solution (1) shows a peak with the same retention time as the principal peak in the chromatogram obtained with solution (2).


Tests

Related substances

Acidity

pH, 4.5 to 5.5, Appendix V L.

Rela ted substances

Carry out the method for liquid chromatography, Appendix III D, using the following solutions.

(1)  Dilute a quantity of the oral suspension with 1% v/v solution of methanolic sulphuric acid to give a solution containing 1.0% w/v of Albendazole and dilute 1 volume of the resulting solution to 2 volumes with the mobile phase. 

(2)  Dilute 1 volume of solution (1) to 100 volumes with mobile phase.

(3)  Dissolve 25.0 mg of albendazole BPCRS and 25.0 mg of oxibendazole BPCRS in 5 ml of 1% v/v solution of methanolic sulphuric acid and dilute to 50 ml with the mobile phase.

chromatographic conditions

(a)  Use a stainless steel column (25 cm × 4.6 mm) packed with end-capped octadecylsilyl silica gel for chromatography (5 µm) (Waters Symmetry is suitable).

(b)  Use gradient elution and the mobile phase described below.

(c)  Use a flow rate of 0.7 ml per minute.

(d)  Use an ambient column temperature.

(e)  Use a detection wavelength of 292 nm.

(f)  Inject 20 µl of each solution.

mobile phase

Mobile phase A  0.015m ammonium dihydrogen orthophosphate.

Mobile phase B  methanol.

VLJTUL6B5M8H423H

System suitability 

The test is not valid unless, in the chromatogram obtained with solution (3), the resolution factor between the two principal peaks is at least 7.0.

limits

In the chromatogram obtained with solution (1):

the area of any secondary peak is not greater than the area of the principal peak in the chromatogram obtained with solution (2) (1%);

the sum of the areas of any secondary peaks is not greater than twice the area of the principal peak in the chromatogram obtained with solution (2) (2%). 

Disregard any peak with an area less than 0.05 times the area of the principal peak in the chromatogram obtained with solution (2) (0.05%).

Assay

Carry out the method for liquid chromatography, Appendix III D, using the following solutions. 

(1)  Add 70 ml of 1% v/v solution of methanolic sulphuric acid to a quantity of the oral suspension containing 0.10 g of Albendazole, stir for 15 minutes, mix with the aid of ultrasound for 10 minutes and add sufficient 1% v/v solution of methanolic sulphuric acid to produce 100 ml. Allow to stand and dilute 5 volumes of the clear supernatant to 25 volumes with 1% v/v solution of methanolic sulphuric acid.

(2)  0.020% w/v of albendazole BPCRS in 1% v/v solution of methanolic sulphuric acid.

chromatographic conditions

The chromatographic conditions described under Related substances may be used.

determination of content

Determine the weight per ml of the oral suspension, Appendix V G, and calculate the content of C12H15N3O2S, weight in volume, using the declared content of C12H15N3O2S in albendazole BPCRS.




The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

Oral Suspension 1Oral Suspension 15Oral Suspension 46

a) Free sample can be supplied.

b) Guide our clients by professional knowledge and teach them how to use our product after sales.

c) Accept SGS,BV any other third-party inspection before loading.

d) High quality best price Guaranteed.


Why do you choose Dideu Industries as your partner?


A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.


B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.


C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.


D)Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.


Dideu Industries is one of the largest producer for general chemical, pharmaceutical, nutrition additive, natural extracts, agrochemical and Daily-Use Chemical in China and is headquartered in Shaanxi, China. The Dideu Group comprises subsidiaries and joint ventures in more than 10 countries and operates six integrated production sites and 21 other production sites in Europe, Asia, Australia, Americas and Africa.Its headquarters is located in Xi’An,China. Dideu has customers in over 200 countries and supplies products to a wide variety of industries.


At the end of 2014, the company employed more than 13000 people. In 2014, Group Dideu posted sales of 30 billion and income from operations before special items of about 7.5 billion. The company is currently expanding its international activities with a particular focus on Asia countries. Between 1990 and 2005, the company invested 5.2 billion in Asia, for example in sites near Guangxi,Yunnan, Sichuan, Shaanxi China,Mangalore in India,Bangkok, Thailand,Hanoi, Vietnam etc.


Dideu Industries Consist Of Five Industry Chains:


I)Pharmaceutical Industries

II)Nutrition Additive Industries

III)Daily-Use Chemical Products Industries & Agrochemicals

IV)Environmental Friendly Chemical And Chemurgy Industries

V)Petrochemical Industries

VI)General Chemical Industry


At Dideu, we redefine chemistry to make the world better - and have been doing so for 75 years. As one of the world's leading chemical company, we combine economic success with environmental protection and social responsibility.Through science and innovation we enable our customers in nearly every industry to meet the current and future needs of society.


At Dideu, we create chemistry for a sustainable future with science for a better life.Dideu is a Life Science company with a long and glorious history and core competencies in the areas of health care and agriculture. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Dideu is improving people's quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality food, feed and plant based raw materials.We develop new molecules for use in innovative products and solutions to improve health. Our research and development activities are based on a profound understanding of the biochemical processes in living organisms.Our goal is to achieve and sustain leadership positions in our markets, thus creating value for our customers, stockholders and employees. To this end, our strategy is designed to help solve some of the most pressing challenges facing humankind, and by doing this exceptionally well we aim to strengthen the company's earning power. 


We are committed to operating sustainably and addressing our social and ethical responsibilities as a corporate citizen, while at the same time respecting the interests of all our stakeholders. Employees with a passion for innovation enjoy excellent development opportunities at Dideu.Exclusive Focus on the Life Science BusinessesFollowing the economic and legal independence of our former Material Science subgroup.Dideu has charted the course for its successful development as a Life Science company. Our Life Science businesses hold leading positions in innovation driven growth markets. Together they make up a strong, attractive and balanced portfolio that is resistant to fluctuations in demand and to potential risks.The previous structure comprising a strategic management holding company and operational subgroups has thus been replaced by an integrated organization under the umbrella of the strong Dideu brand. The company's operations are managed in three divisions Pharmaceuticals, Consumer Health and Crop Science and the Animal Health business unit.The business continues to be supported by the corporate functions, Dideu Business Services and the service company Currenta, while Technology Services is being integrated into Dideu Group, forming the Engineering and Technology function.


Quality≥1000Unit,please send inquire:
Online Service

Product Inquiry

Customer Reviews

Trade Alert - Delivering the latest product trends and industry news straight to your inbox.
Customer Services
About Us
Chemicalorigin
Trade Services
 ©2020 Dideu Industries Group Limited